Four-year follow-up of treatment with intramyocardial skeletal myoblasts injection in patients with ischaemic cardiomyopathy
نویسندگان
چکیده
منابع مشابه
Four-year follow-up of treatment with intramyocardial skeletal myoblasts injection in patients with ischaemic cardiomyopathy.
AIMS Studies reporting improved left ventricular (LV) function of percutaneous skeletal myoblast (SkM) injection in patients with ischaemic cardiomyopathy had follow-up not exceeding 12 months, and did not include a control group. Our group has reported evidence for myoblast efficacy in the first five out of the 14 treated patients. The objective of the present evaluation was to assess if these...
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چکیده ندارد.
15 صفحه اولSafety and feasibility of autologous myoblast transplantation in patients with ischemic cardiomyopathy: four-year follow-up.
BACKGROUND Successful autologous skeletal myoblast transplantation into infarcted myocardium in a variety of animal models has demonstrated improvement in cardiac function. We evaluated the safety and feasibility of transplanting autologous myoblasts into infarcted myocardium of patients undergoing concurrent coronary artery bypass grafting (CABG) or left ventricular assist device (LVAD) implan...
متن کاملCell Transplantation Catheter-Based Intramyocardial Injection of Autologous Skeletal Myoblasts as a Primary Treatment of Ischemic Heart Failure Clinical Experience With Six-Month Follow-Up
OBJECTIVES We report on the procedural and six-month results of the first percutaneous and stand-alone study on myocardial repair with autologous skeletal myoblasts. BACKGROUND Preclinical studies have shown that skeletal myoblast transplantation to injured myocardium can partially restore left ventricular (LV) function. METHODS In a pilot safety and feasibility study of five patients with symp...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2008
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehn171